Endothelial Function Improved after Active Mattress Use
Introduction:
Endothelial dysfunction, a significant contributor to cardiovascular conditions, plays a critical role in the development of pressure injuries (1,2,3,4). Studies indicate that endothelial function is significantly worse in individuals with a history of pressure injuries (2). This study aims to investigate whether eight weeks of active mattress use, which has been shown to reduce the incidence of pressure injuries, can improve endothelial function.
Methods:
Participants resting blood flow (RBF), and endothelial function (measured using post-occlusive reactive hyperemia - PORH) (Fig 1), were assessed at:
- Baseline (Week 0)
- After 8 weeks of active mattress use
- After an 8-week washout period (Week 16)
The study included 10 healthy individuals (4 males, age 52.7±8.5 years; 6 females, age 51.8±17.5 years).
Results:
- ·Resting Blood Flow (RBF): Increased by 336% (24.3±38.3 to 106.0±100.3 perfusion units, p=0.021) (Fig 2).
- ·Endothelial Function (PORH): Improved by 197% (13,456±10,225 to 40,252±23,995 perfusion units x seconds, p=0.003).
Conclusions:
Eight weeks of active mattress use significantly improved endothelial function and resting blood flow in the skin, demonstrating notable enhancements in skin function and health and highlighting their potential in reducing pressure injuries.
Future research should explore the additional benefits of active mattresses in managing endothelial dysfunction and related disorders.
Research Conducted by
University of St Mark & St John
Research Published by the Journal of Wound Care.
Research Pubished by PUB MED.
