Improve Endothelial Function

Squirrel mattresses have been shown to improve endothelial function, 197% just by going to sleep.

· Endothelial dysfunct,Endothelium,Treat endothelial dy,poor circulation,poor blood flow

Endothelial dysfunction is a growing concern in today's society, as it has been linked to a wide range of health conditions, including long COVID-19 (1,4), sleep disorders, (2) cognitive decline (3), deep vein thrombosis (4)atherosclerosis (5), hypertension (6) and metabolic disorders (7). To address this growing problem, researchers have been investigating new and innovative ways to improve endothelial function. One such approach is the use of vestims mattresses.

Vestims mattresses are designed to prevent, treat, and relieve pressure ulcers by providing intermittent contact pressure and relief. However, recent studies have shown that vestims mattresses can also have a positive impact on endothelial function.(8) For example, a study published in the Journal of Wound Care, found that eight weeks of vestims mattress use led to significant improvements in baseline skin temperature, resting blood flow, and endothelial function as measured using post-occlusive revestims hyperaemia (PORH) in healthy participants. (8)

The study recruited 10 healthy participants and found that following vestims mattress use, resting blood flow, PORH, and baseline skin temperature at the big toe increased by 336%, 197%, and 3.5ºC, respectively. (7) These results demonstrate that vestims mattress use improves endothelial function.

One of the key benefits of vestims mattress use is that it is a non-clinical intervention and can be undertaken in the domestic household, it requires no additional exercise or dietary intervention, making it convenient and accessible for patients. This means that it can be used by a wide range of individuals, including those who may not be able to participate in other forms of treatment.

However, it is also important to note that vestims mattress use may not be effective for all individuals with endothelial disorders, and should be used in conjunction with other treatments. Therefore, it is recommended that patients with endothelial disorders consult with their healthcare provider to determine the best course of treatment for their individual needs.

In conclusion, vestims mattress use is a promising new approach to treating endothelial dysfunction. 


1. Charfeddine S, Ibn Hadj Amor H, Jdidi J, Torjmen S, Kraiem S, Hammami R, Bahloul A, Kallel N, Moussa N, Touil I, Ghrab A, Elghoul J, Meddeb Z, Thabet Y, Kammoun S, Bouslama K, Milouchi S, Abdessalem S, Abid L. Long COVID 19 Syndrome: Is It Related to Microcirculation and Endothelial Dysfunction? Insights From TUN-EndCOV Study. Front Cardiovasc Med. 2021 Nov 30;8:745758. doi: 10.3389/fcvm.2021.745758. PMID: 34917659; PMCID: PMC8670225.

2. Holmer BJ, Lapierre SS, Jake-Schoffman DE, Christou DD. Effects of sleep deprivation on endothelial function in adult humans: a systematic review. Geroscience. 2021 Feb;43(1):137-158. doi: 10.1007/s11357-020-00312-y. Epub 2021 Feb 9. PMID: 33558966; PMCID: PMC8050211 

3. Saleem M, Herrmann N, Dinoff A, Mazereeuw G, Oh PI, Goldstein BI, Kiss A, Shammi P, Lanctôt KL. Association Between Endothelial Function and Cognitive Performance in Patients With Coronary Artery Disease During Cardiac Rehabilitation. Psychosom Med. 2019 Feb/Mar;81(2):184-191. doi: 10.1097/PSY.0000000000000651. PMID: 30383709; PMCID: PMC6365250. 

4. Elyaspour Z, Zibaeenezhad MJ, Razmkhah M, Razeghian-Jahromi I. Is It All About Endothelial Dysfunction and Thrombosis Formation? The Secret of COVID-19. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211042940. doi: 10.1177/10760296211042940. PMID: 34693754; PMCID: PMC8543709. 

5Davignon J, Ganz P. Role of endothelial dysfunction in atherosclerosis. Circulation. 2004 Jun 15;109(23 Suppl 1):III27-32. doi: 10.1161/01.CIR.0000131515.03336.f8. PMID: 15198963. 

6.Konukoglu D, Uzun H. Endothelial Dysfunction and Hypertension. Adv Exp Med Biol. 2017;956:511-540. doi: 10.1007/5584_2016_90. PMID: 28035582. 

7. Tziomalos K, Athyros VG, Karagiannis A, Mikhailidis DP. Endothelial dysfunction in metabolic syndrome: prevalence, pathogenesis and management. Nutr Metab Cardiovasc Dis. 2010 Feb;20(2):140-6. doi: 10.1016/j.numecd.2009.08.006. Epub 2009 Oct 14. PMID: 19833491. 

8. Baker G, Bloxham S, Laden J, Gush R. Vascular endothelial function is improved after active mattress use. J Wound Care. 2019 Oct 2;28(10):676-682. doi: 10.12968/jowc.2019.28.10.676. PMID: 31600104.